Computer-aided Formulation Development for Small Molecule Drugs and Biologics

12:25 - 13:00

  • Practical utilization of molecular modeling to provide theoretical backing and inform decision making in drug formulation that compliments experimental data
  • API and excipient property prediction for small molecule drug formulations
  • Characterization of drug-drug and drug-polymer association in small molecule formulations including amorphous solid dispersions
  • Predict viscosities and provide structural insights into concentrated globular protein and antibody solutions including excipient effects

John C. Shelley, Schrödinger Fellow, Schrödinger