- Demonstrate connection between ASD thermodynamic properties and HME manufacturing process
- Application drug/polymer phase diagram as a tool for HME risk assessment
- Demonstrate correlation between drug/polymer phase diagram, drug load, rheology, and HME process.
- Correlating drug product CQA (residual crystallinity, chemical/thermal stability) to drug/polymer phase diagram and HME process parameters
Samuel Kyeremateng, NCE Formulation Sciences Senior Scientist, Abbvie