Challenging Transfer of a Fill & Finish Process for a Highly Fragile Bispecific mAb

11:45 - 12:20

  • Utility of extensive comprehension of the mAb aggregation law
  • Set-up of a temperature control process to prevent aggregation
  • Impact of temperature variations on fill weights during Time-pressure filling

Stephanie Greco, Head of laboratory in Formulation & Process Development, Sanofi