The unmet need of biodegradable parenteral controlled release DDS: concept, performance and perspectives

3/12/2018 16:05 - 16:35

  • Parenteral CR is dominated by PLA and PLGA based DDS
  • Many clinically used DDS have undesired release profiles (very high burst release or lag times, complex release profiles)
  • Problems are associated with high acidity of PLA / PLGA monomers
  • Alternatives are needed to increase selection portfolio
  • Promising alternatives will be presented (lipid and polymer based)

Prof. Dr. Karsten Mäder, Head of Pharmaceutical Technology, Martin Luther University Halle-Wittenberg